Website of Dr. Joseph George

Ryuichi Kubota, Nobuhiko Hayashi, Mutsumi Tsuchishima, Mikihiro Tsutsumi and Joseph George. Inhibition of g-glutamyl transpeptidase ameliorates hepatic ischemia/reperfusion injury in rats with fatty liver.

Journal of Hepatology 2020; 73 (Suppl 1): S286. doi: 10.1016/S0168-8278(20)31077-1 (JCR Impact Factor 2020 = 25.083)

Joseph George, Yuki Hirakawa, Atsushi Fukumura, Mutsumi Tsuchishima, and Mikihiro Tsutsumi: Recombinant thrombomodulin prevented hepatic ischemia-reperfusion injury by inhibiting high-mobility group box 1 in rats.

Gastroenterology 2020; 158 (Suppl 1): S-1340. doi: 10.1016/S0016-5085(20)34019-1 (JCR Impact Factor 2020 = 22.682)

Joseph George, Takashi Saito, Nobuhiko Hayashi, Mutsumi Tsuchishima, and Mikihiro Tsutsumi. Serum miRNA-320 as a potent diagnostic biomarker for human hepatocellular carcinoma irrespective of etiology.

Hepatology International 2020; 14 (Suppl 1): S234 doi: 10.1007/s12072-020-10030-4 (JCR Impact Factor 2020 = 6.047)

Joseph George, Atsushi Fukumura, Kazuaki Ozaki, Nobuyuki Toshikuni, Mutsumi Tsuchishima, and Mikihiro Tsutsumi: Diagnostic and prognostic implication of miR-27a-3p in human hepatocellular carcinoma with different etiology.

Gastroenterology 2019; 156 (Suppl 1): S-1314. doi: 10.1016/S0016-5085(19)40300-4 (JCR Impact Factor 2020 = 22.682)

Joseph George, Takashi Saito, Nobuhiko Hayashi, Kazuaki Ozaki, Mikihiro Tsutsumi, and Mutsumi Tsuchishima: SPP1 gene knockout in human hepatic stellate cells decreased profibrogenic cytokines and collagen gene expression.

Journal of Hepatology 2019; 70 (Suppl 1): e193. doi: 10.1016/S0618-8278(19)30357-3 (JCR Impact Factor 2020 = 25.083)

Joseph George, Nobuhiko Hayashi, Takashi Saito, Mikihiro Tsutsumi, and Mutsumi Tsuchishima: Targeted delivery of chemotherapeutic agents employing nanovesicles effectively reduced intrahepatic tumors.

Cancer Research 2019; 79 (13 Suppl): Abstract nr 2178. doi: 10.1158/1538-7445.AM2019-2178 (JCR Impact Factor 2020 = 12.701)

Joseph George,Takahiro Minato, Yasuhiro Matsue, Yuki Hirakawa, Mikihiro Tsutsumi, and Mutsumi Tsuchishima. Combination treatment with epigallocatechin gallate and silibinin restored antioxidant defense mechanisms and prevented N-nitrosodimethylamine induced  hepatic fibrosis in rats.

Hepatology International 2019; 13 (Suppl 1): S128–S129 doi: 10.1007/s12072-019-09936-5 (JCR Impact Factor 2020 = 6.047)

Joseph George, Nobuhiko Hayashi, Mikihiro Tsutsumi, and Mutsumi Tsuchishima:
Targeted delivery of epigallocatechin gallate and anti-mir221 regressed intrahepatic tumors in athymic mice.

Gastroenterology 2018; 154 (Suppl 1): S1154. doi:10.1016/S0016-5085(18)33823-X(JCR Impact Factor 2020 = 22.682)

Akiko Matsuda, Sayantan Maji, Joseph George, Irene Yan, Tushar Patel: Hepatic delivery of therapeutic agents using biological nanoparticles.

Gastroenterology 2017; 152 (Suppl 1): S298-S299. doi: 10.1016/S0016-5085(17)31286-6 (JCR Impact Factor 2020 = 22.682)

Joseph George, Nobuhiko Hayashi, Mutsumi Tsuchishima and Mikihiro Tsutsumi: Inhibition of g-Glutamyl transpeptidase attenuates hepatic ischemia-reperfusion injury in rats.

Gastroenterology 2017; 152 (Suppl 1): S-559. doi: 10.1016/S0016-5085(17)32026-7 (JCR Impact Factor 2020 = 22.682)

Cancer Research 2017; 77 (13 Suppl): Abstract nr 2165. doi: 10.1158/1538-7445.AM2017-2165 (JCR Impact Factor 2020 = 12.701)

Joseph George, Nobuhiko Hayashi, Takashi Saito, Kazuaki Ozaki, Nobuyuki Toshikuni, Mutsumi Tsuchishima and Mikihiro Tsutsumi. Nanovesicle mediated delivery of combination of anticancer agents effectively induced cell death in Hepatocellular carcinoma cell lines.

Journal of Hepatology 2017; 66 (Suppl 1): S462. doi: 10.1016/S0168-8278(17)31308-9 (JCR Impact Factor 2020 = 25.083)

Hepatology 2014; 60 (Suppl S1): 583A. (Abstract nr. 794) doi: 10.1002/hep.27513 (JCR Impact Factor 2020 = 17.425)

Cancer Research 2013; 73 (8 Suppl): Abstract nr. 3584. doi:10.1158/1538-7445.AM2013-3584 (JCR Impact Factor 2020 = 12.701)

Alcoholism: Clinical and Experimental Research 2012; 36 (Suppl S2): 59A. doi: 10.1111/j.1530-0277.2012.01917.x (JCR Impact Factor 2020 = 3.455)

Mutsumi Tsuchishima, Joseph George, Hisakazu Siroeda, Takashi Saito, Tomiyasu Arisawa and Mikihiro Tsutsumi. Mechanism of the pathogenesis of hepatocellular carcinoma during chronic administration of ethanol in mice.

Hepatology 2011; 54 (Suppl S1): 1300A-1301A. (Abstract nr. 1999) doi: 10.1002/hep.24666 (JCR Impact Factor 2020 = 17.425)

Hepatology 2011; 54 (Suppl S1): 1223A. (Abstract nr. 1828) doi: 10.1002/hep.24666 (JCR Impact Factor 2020 = 17.425)

Hepatology International 2011; 5 (1): 296–297. doi: 10.1007/s12072-010-9241-z (JCR Impact Factor 2020 = 6.047)

Hepatology 2010; 52 (Suppl S1): 453A. (Abstract nr. 260) doi: 10.1002/hep.23979 (JCR Impact Factor 2020 = 17.425)

Hepatology 2010; 52 (Suppl S1): 1260A-1261A. (Abstract nr. 1977) doi: 10.1002/hep.23997 (JCR Impact Factor 2020 = 17.425)

Hepatology 2010; 52 (Suppl S1): 1053A. (Abstract nr. 1531) doi: 10.1002/hep.23995 (JCR Impact Factor 2020 = 17.425)

Hepatology 2010; 52 (Suppl S1): 1284A. (Abstract nr. 2032) doi: 10.1002/hep.23997 (JCR Impact Factor 2020 = 17.425)

Cancer Research 2010; 70 (8 Suppl): Abstract nr 681. doi: 10.1158/1538-7445.AM10-681 (JCR Impact Factor 2020 = 12.701)

Cancer Research 2010; 70 (8 Suppl): Abstract nr 578. doi: 10.1158/1538-7445.AM10-578 (JCR Impact Factor 2020 = 12.701)

Hepatology 2009; 50 (Suppl 4): 823A-824A. (Abstract nr. 1111) doi: 10.1002/hep.23305  (JCR Impact Factor 2020 = 17.425)

Cancer Research 2009; 69 (9 Supplement): Abstract nr 4662. doi: 69/9_Supplement/4662 (JCR Impact Factor 2020 = 12.701)

Journal of Neurochemistry 2009; 108 (Suppl 1): 92-93. doi: 10.1111/j.1471-4159.2009.05818.x (JCR Impact Factor 2020 = 5.372)

Hepatology 2008; 48 (Suppl S1): 912A-913A. (Abstract nr. 1355) doi: 10.1002/hep.22646 (JCR Impact Factor 2020 = 17.425)

Hepatology 2008; 48 (Suppl S1): 929A-930A. (Abstract nr. 1396) doi: 10.1002/hep.22646 (JCR Impact Factor 2020 = 17.425)

Joseph George, Stephen Tomlinson, Naren L. Banik and Swapan K. Ray. Synergistic effect of Bcl-xL small interfering RNA and genistein in human neuroblastoma SH-SY5Y and SK-N-DZ cells for induction of apoptosis and inhibition of angiogenesis and tumor growth in nude mice.

Cancer Research 2008; 68 (9 Suppl): Abstract nr 4406. doi: 68/9_Supplement/4406 (JCR Impact Factor 2020 = 12.701)

Joseph George, Naren L. Banik and Swapan K. Ray. siRNA mediated knockdown of Bcl-2 and low-dose taxol treatment in human glioblastoma U251MG cells induces apoptosis, inhibits cell invasion, angiogenesis, and tumor growth in nude mice.

Cancer Research 2008; 68 (9 Suppl): Abstract nr 4389. doi: 68/9_Supplement/4389 (JCR Impact Factor 2020 = 12.701)

Joseph George, James S. Norris, Naren L. Banik and Swapan K. Ray. Simultaneous siRNA mediated downregulation of hTERT and treatment with interferon-gamma in human glioblastoma SNB-19 and LN-18 cells causes cell cycle arrest and inhibits invasion, angiogenesis, and tumor growth in nude mice.

Cancer Research 2008; 68 (9 Suppl): Abstract nr 1834. doi: 68/9_Supplement/1834 (JCR Impact Factor 2020 = 12.701)

Joseph George, Naren L. Banik, Swapan K. Ray. siRNA-mediated knockdown of Bcl-2 in human glioblastoma cell lines increased taxol-mediated apoptosis.

Journal of Neurochemistry 2007; 102 (Suppl 1): 259. Abstract nr P.389 doi: 10.1111/j.0022-3042.2007.04730.x (JCR Impact Factor 2020 = 5.372)

Cancer Research 2006; 66 (8 Suppl): Abstract nr 957. doi: 66/8_Supplement/226.2 (JCR Impact Factor 2020 = 12.701)

Joseph George, Kazuki Nemoto, Teruo Miyata and Yoshinori Kuboki: Honeycomb collagen scaffold for the in vitro differentiation of mesenchymal stem cells into osteoblasts.

Tissue Engineering 2002; 8 (6): 1245-1246. doi: 10.1089/107632702320934236 (JCR Impact Factor 2020 = 3.845)

Kazuki Nemoto, Hiroko Takita, Ryota Yoshimoto, Joseph George, Teruo Miyata and Yoshinori Kuboki: Geometry of honeycomb collagen scaffold gives chamber type microenvironmental units for ectopic osteogenesis when implanted with purified BMP cocktail into rat skin.

Tissue Engineering 2002; 8(6): 1148-1149. doi: 10.1089/107632702320934227 (JCR Impact Factor 2020 = 3.845)

Joseph George, Mikihiro Tsutusmi and Shujiro Takase. Expression of TIMP-1 and TIMP-2 in N-nitrosodimethylamine induced hepatic fibrosis in rats.

Hepatology 2000; 32 (4 Part 2): 505A-505A. (Abstract nr. 1381) (JCR Impact Factor 2020 = 17.425)

Joseph George, Mikihiro Tsutsumi, Chen Wunbill, Mutsumi Tsuchishima and Shujiro Takase: Mechanism of the increased serum hyaluronic acid in rats treated with N-nitrosodimethylamine.

Journal of Gastroenterology and Hepatology 2000; 15 (Suppl): F74. (JCR Impact Factor 2020 = 4.029)

Joseph George and Gowri Chandrakasan: Collagen metabolism in dimethylnitrosamine induced hepatic fibrosis in rats.

FASEB Journal 1997; 11 (9 Suppl S) A1094. (JCR Impact Factor 2020 = 5.191)

Joseph George and Gowri Chandrakasan: Structural and functional alterations in liver during fibrosis.

ICMR Bulletin 1996; 26: 36-37. (JCR Impact Factor 2020 = 2.375)

Immunology and Cell Biology 1995; 73A14. (JCR Impact Factor 2020 = 5.126)